Category: Extramural Funding

This topic encourages research on the interaction of GLP-1s and nutrient metabolism and status, and population health and the roles of dietary supplements in addressing nutrient gaps that may arise with GLP-1 use, as well as on the composition, safety, and usage patterns, and biological mechanisms of supplements marketed to mimic GLP-1 activity. Participating Institutes and Centers include NIDDK and NIA. [Expires 4/24/28.]

This Highlighted Topic encourages research that improves validity and reliability of findings by enhancing rigorous and transparent experimental design, methodology, analysis, and interpretation. Participating Institutes and Centers include NIDDK, NIA, NIAID, NINDS, and NICHD. [Expires 4/27/28.]

The NIH Health and Extreme Weather (HEW) Program aims to support research to increase understanding of how extreme weather, including weather-related natural disasters and emerging weather-related harms, impacts human health. Participating Institutes and Centers include NIDDK, NIA, and NIAID. Relevant areas of study include effects of discontinuity of care, changes in aging-related processes and responses, immune responses, and pathogens. [Expires 5/1/28.]

This topic encourages innovative research on human-relevant new approach methodologies (NAMs) (e.g., organoids, tissue chips, microphysiological systems, multi-omics technologies, computational models) to evaluate the safety and efficacy of foods, food components, and dietary supplements for health optimization and chronic disease risk reduction across the lifespan. Participating Institutes and Centers include NIDDK and NIA. [Expires 5/20/28.]

This Highlighted Topic encourages rigorous, innovative research in utilizing publicly accessible, high-quality datasets. The ultimate goal is to enhance reproducibility, enable data-driven hypothesis generation, accelerate scientific discovery, and improve disease prevention, diagnosis, treatment, and patient outcomes. Participating Institutes and Centers include NIDDK, NIA, and NIAID. [Expires 6/24/28.]

A digital twin is a set of virtual information constructs that mimics the structure, context, and behavior of a natural, engineered, or social system (or system-of-systems), is dynamically updated with data from its physical twin, has a predictive capability, and informs decisions that realize value. This topic encourages innovative research and prototype development of digital twin technologies. Participating Institutes and Centers include NIDDK and NIAID. [Expires 9/10/28.]

NIDDK encourages R01 research applications responding to this Topic to be limited in scope (a tightly focused central aim) and duration (1-3 years) to establish proof-of-concept, validate model prototyping, and demonstrate the feasibility of adopting microphysiological systems in the study of diabetes and diabetic kidney and urologic complications. [Expires: 9/10/28.]

The NIH encourages investigators to submit proposals to existing funding announcements for research that may address health behavior initiation, execution, and/or maintenance through mechanistic studies, efficacy trials, or implementation science research. Participating Institutes and Centers include NIDDK, NIA, and NIAID. [Expires 9/15/28.]

This NIH Highlighted Topic encourages researchers to utilize specific existing research resources in research project grants (RPGs), with the goal of generating new insights into disease mechanisms, prevention, diagnosis, and treatment. Participating institutes include NIDDK and NIA. [Expires 9/16/28.]