Up to 5 years support for translational activities and clinical studies to advance the development of medical devices for disease prevention, monitoring, diagnosis, and treatment. Supports implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities leading to either a submission of an Investigational Device Exemption (IDE) to the FDA or IRB approval. Subsequent clinical studies, feasibility or pivotal trials, as appropriate, may be supported. Expires January 29, 2028.