PAR-27-022: Invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. Awards range from $300K to $5m. Cost sharing is required for premium instruments or special use instruments.

Upcoming due dates: July 27, 2026; July 1, 2027; July 1, 2028.

Expires July 2, 2028.