This topic is being issued as part of the Make America Healthy Again initiative. This is not a notice of funding opportunity (NOFO).

This topic encourages innovative research on human-relevant new approach methodologies (NAMs) (e.g., organoids, tissue chips, microphysiological systems, multi-omics technologies, computational models) to evaluate the safety and efficacy of foods, food components, and dietary supplements for health optimization and chronic disease risk reduction across the lifespan.

Participating Institutes and Centers include NIDDK* and NIA.

*NIDDK may give special consideration to support meritorious applications in this topic area.

Expires May 20, 2028.