University of Pennsylvania – Institute for Translational Medicine and Therapeutics (ITMAT) Funding

PICAB Program in Comparative Animal Biology

The Institute for Translational Medicine and Therapeutics – Clinical and Translational Science Award (ITMAT-CTSA) Program in Comparative Animal Biology (PICAB) is accepting applications for a pilot grant program between the School of Veterinary Medicine (SVM) and the Perelman School of Medicine (PSOM) aimed at better understanding of the mechanisms of pathology in animal diseases that are appropriate models for human diseases.  The purpose is to facilitate interdisciplinary investigations between comparative and human medical scientists to advance understanding of diseases. The project must have one co-PI from the School of Veterinary Medicine, and one co-PI from the Perelman School of Medicine. Additional faculty may be part of a proposal as co-investigators. Projects may be in any area of medicine. Two pilot grants of up to $30,000 each is available start date of February 1, 2026. Grants are due at noon on Wednesday, December 3, 2025 at 12PM ET.

TBIC Translational Biomedical Imaging Center

In pursuit of its mission to broaden and accelerate translational imaging research through the development of a center to bring together investigators with diverse backgrounds that contribute to various aspects of imaging science and who share a vision of contributing to the advancement of clinical medicine, the TBIC is accepting applications for its collaborative pilot grant program to help catalyze collaborations between primary imaging scientists and primary biomedical/clinical researchers that integrate novel imaging approaches to enhance translational science and medicine. These proposals require at least two Co-Principal Investigators, one investigator whose primary research focus is in imaging methodology development and another investigator whose research is focused on biomedical science. At least one of the co-principal investigators should have a primary appointment in the School of Medicine. The TBIC adopts a broad definition of imaging science and seeks proposals that focus on anatomic or functional imaging approaches that span from the microscopic to in vivo regimes. Proposals that include a broad range of imaging methods including image acquisition techniques, image analysis, imaging probe development will be considered. Funding will be based on scientific merit, potential downstream clinical impact and the likelihood that the project will generate independent funding to sustain the effort. Post-pilot award outcomes will be surveyed. The deadline for applications is December 4, 2025, for an award start date of March 1, 2026.

TAPITMAT Transdisciplinary Awards Program in Translational Medicine and Therapeutics

The Institute for Translational Medicine and Therapeutics (ITMAT), home of the CTSA invites proposals from ITMAT Members and ITMAT Associate Members in the Research Associate or Instructor A category or higher. If you are interested, please visit the membership webpage for details. The proposals must center on the translational space – from proof of concept in cells or model systems through to mechanistic studies in humans elucidating human physiology or mechanisms of disease or, in drug development, parsing sources of variability in drug response and/or understanding mechanisms of drug action in humans in Phase II. Programs that plan to progress within that space and which deploy technologies and approaches conventionally segregated from each other within the traditional boundaries of academic medicine will be especially favored. Proposals that focus on translational therapeutics or on bridging the pediatric to adult divide are particularly encouraged. Proposals are due December 5, 2025, for a proposal start date of February 1, 2026.  LATE SUBMISSIONS WILL NOT BE ACCEPTED NOR WILL EXTENSIONS BE GRANTED.

Updated October 31, 2025.