CAIRIBU U-RIG Research Hour: Bridging Knowledge Gaps in the Urobiome

The Uromicrobiota Research Interest Group (U-RIG) includes CAIRIBU and non-CAIRIBU investigators interested in the uromicrobiota. Investigators are clinicians and scientists from a variety of fields including urology, urogynecology, microbiology, microbial ecology, virology, bioinformatics, and computer and data science.

The CAIRIBU U-RIG Research Hour aims to facilitate knowledge exchange and spur collaborations in the urobiome and adjacent fields

U-RIG Research Hour Series

UPCOMING U-RIG MEETINGS:

SEPTEMBER 29 @ 3PM EDT – CAIRIBU Connections: Elevating the Patient Voice in UTI Research – A Clinician Scientist Panel
OCTOBER 20 @ 3 PM EDT – CAIRIBU U-RIG Research Hour: Bridging Knowledge Gaps in the Urobiome
Sub-groups are forming to collaborate in various research and writing projects. Contact CAIRIBU@urology.wisc.edu for more information or to get plugged in.

PRIOR U-RIG MEETINGS:

EXECUTIVE SUMMARY – September 2023 U-RIG Research Hour, featuring Aaron Miller, PhD (Cleveland Clinic) and Lindsey Burnett, MD, PhD, University of California San Diego) HERE
SUMMARY of discussions in 2023, through July, HERE
REVIEW of plans discussed up to January 2022 HERE

View CAIRIBU Connections: “UTI Through the Lifespan – A Patient Perspective”

CAIRIBU Connections are virtual gatherings that aim to bring together CAIRIBU and non-CAIRIBU investigators interested in similar topics. This CAIRIBU Connections topic of “UTI Through the Lifespan – A Patient Perspective” was formatted as a patient panel. This event aimed to shed light on urinary tract infections (UTIs) from a unique standpoint – that of the patients themselves. Patient panelists from the UTI Health Alliance patient advocacy group covered viewpoints from early childhood, parenting a young child with UTI, young adulthood with UTI, middle age, and postmenopausal. This event was curated to build pathways for knowledge exchange between patients and researchers and provide investigators with the tools to develop patient-centered research agendas around the topic of UTIs.

Conceptual “mind map” of knowledge gaps, barriers, and challenges in urinary microbiota research

Generated from discussion at the July 2021 kickoff CAIRIBU U-RIG Meeting

RESOURCES:

YouTube video, CAIRIBU Connections: “UTI Through the Lifespan – A Patient Perspective” (2023)
“Beyond the usual suspects: emerging uropathogens in the microbiome age,” including co-authors Brubaker and Wolfe in Frontiers in Urology (2023)
“Tarnished gold—the “standard” urine culture: reassessing the characteristics of a criterion standard for detecting urinary microbes,” by Brubaker et al. in Frontiers in Urology (2023)
Review paper, “The Human Urobiome,” by Brubaker, Putonti, Dong, and Wolfe in Mammalian Genome (2021)
Consensus paper on advancing urobiome research by Brubaker et al. in mSystems (2021)
Consensus paper on microbiome studies for urolithiasis by Khachroo et al in Nature Reviews Urology (2021)
“Urinary Tract Infection” – Requiem for a Heavyweight by Finucane in J Am Geriatr Soc (2017)
“The Kidney: A filter for bacteria,” by Helmholz and Millikin inThe American Journal of Diseases of Children (1925)
Talk on urobiome metadata standards by Dr. Lisa Karstens (recorded 2022)
List of publications on urinary microbiota by CAIRIBU U-RIG Attendees. Note that this list is NOT exhaustive. Currently, it includes relevant publications by participants of the 2021-2023 CAIRIBU Connections discussions on the urobiome. This will be updated over time.