NIA Multi-site Clinical Trial Implementation Grant (R01 Clinical Trial Required). This Notice of Funding Opportunity (NOFO) invites applications for implementation of investigator-initiated multi-site interventional clinical trials (all phases). The trials should be hypothesis-driven, milestone-defined, and related to NIA’s research mission. Information about NIA’s mission can be found on the NIA website. [Posted on 11/6/2024. Expires on 1/8/2026]
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Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)
Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed). This Notice of Funding Opportunity (NOFO) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) and related assays that replicate complex nervous system architectures and physiology with improved fidelity over current capabilities. Supported projects will be expected to enable future studies of complex nervous system development, function and aging in healthy and disease states. [Posted 11/6/2024. Expires on 1/8/2026]
Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed)
Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed). This Notice of Funding Opportunity (NOFO) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) and related assays that replicate complex nervous system architectures and physiology with improved fidelity over current capabilities. Supported projects will be expected to enable future studies of complex nervous system development, function, and aging in healthy and disease states. [Posted 11/6/2024. Expires 1/8/2026]
Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33 Clinical Trial Optional)
Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33 Clinical Trial Optional). This NOFO invites applications that propose advanced-stage development and utilization of novel research infrastructure to advance the science of aging in specific areas requiring interdisciplinary partnerships or collaborations. Applicants are expected to have an existing research infrastructure developed with other NIH or non-NIH support. Through this award, investigators will endeavor to develop a mature and sustainable research infrastructure to support projects that address key interdisciplinary aging research questions. [Posted 11/2/2024. Expires 12/3/2025]
Innovative Interdisciplinary Research on Female Reproductive Aging
Innovative Interdisciplinary Research on Female Reproductive Aging. NIA is issuing this notice to encourage innovative interdisciplinary research on the molecular, cellular, and physiological processes involved in female reproductive aging, with the goal to identify and understand key biological pathways involved in aging associated health outcomes in women across the lifespan. Interdisciplinary research that integrates knowledge, expertise, and perspectives from different disciplines may help to give a more complete understanding of the biological drivers of female reproductive aging, as well as provide novel insights into the complexity of overall aging in females. [Posted 12/11/2024. Expires 5/8/2028]
Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional) This Notice of Funding Opportunity is intended to identify and support research projects by exceptionally promising Early Stage Investigators with a long-term career interest in pursuing innovative research in genomics. This opportunity is open to research in all areas relevant to the mission of NHGRI, including genomic sciences, genomic medicine, genomic data science, and ethical, legal, and social implications (ELSI) of genomics. [Posted 12/16/2024. Expires 2/27/2027]
Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)
Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional) The Joint NINDS/NIMH Exploratory Neuroscience Research Grant program supports exploratory and innovative research projects, which fall within the missions of the NINDS and NIMH. Awards will provide support for the early and conceptual stages of projects. [Posted 1/8/2025. Expires 1/8/2028]
Joint NINDS/NIMH Exploratory Neuroscience Research Grant (R21 Clinical Trial Not Allowed)
Joint NINDS/NIMH Exploratory Neuroscience Research Grant (R21 Clinical Trial Not Allowed) The Joint NINDS/NIMH Exploratory Neuroscience Research Grant program supports exploratory and innovative research projects, which fall within the missions of the NINDS and NIMH. [Posted 1/8/2025. Expires 1/8/2025]
Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3 Clinical Trial Not Allowed)
Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3 Clinical Trial Not Allowed) The purpose of this Notice of Funding Opportunity (NOFO) is to encourage grant applications for investigator-initiated prospective observational comparative effectiveness research (CER) to the National Institute of Neurological Disorders and Stroke (NINDS) (note: only prospective observational studies will be considered). [Posted 1/8/2025. Expires 9/8/2025]
Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed)
Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed) This Notice of Funding Opportunity (NOFO) establishes an accelerated review/award process to support time-sensitive research to evaluate a new policy or program that is likely to influence diet, physical activity, sleep, and/or weight and thus has the potential to lower rates of chronic diseases, particularly in populations at risk for health disparities. [Posted 1/10/2025. Expires 1/12/2028]