About

The Peer Reviewed Medical Research Program (PRMRP) is part of the US Department of Defense’s Congressionally Directed Medical Research Programs. The portfolio for this program includes, but is not limited to, the following topics which may be relevant to urologic research:

• Autoimmune disorders and immunology
  • Inflammatory Bowel Disease
• Internal Medicine
  • Accelerated Aging Processes Associated with Military Service, Interstitial Cystitis, Infertility Associated with Military Aviators and Aviation Support Personnel
• Research and Clinical Tools
  • Proteomics

This program encompasses 7 funding mechanisms supporting research across the translational spectrum.

Basic Research:

Discovery Award (HT942526PRMRPDA) supports novel, high-risk, high reward research projects with the potential to yield high-impact findings and new avenues of investigation. Preliminary data is not allowed.

Research Advancement Award (HT942526PRMRPRAA) supports fundamental research studies that will make an important contribution towards research, patient care, and/or quality of life and building upon existing preliminary data to validate a concept.

Translational Research

Impact Award (HT942526PRMRPIPA) supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research and insights from the real-world environment to foster clinical applicability.

Technology/Therapeutic Development Award (HT942526PRMRPTTDA) for finalizing preclinical development of tangible products (drugs or biologics), knowledge-based products and/or devices. The research outcome should be a regulatory filing or translation of findings into clinical practice, as applicable. Applications must include preliminary data demonstrating proof-of-concept for the product.

Translational to Clinical Transition Research

Platform Clinical Translation Award (HT942526PRMRPPCTA) for finalizing preclinical development, conducting clinical validation studies, and/or conducting first in human clinical trials for a platform product with the potential to impact clinical care for two or more FY26 PRMRP topic areas.

Clinical Research

Lifestyle and Applied Health Research Award (HT942526PRMRPLAHRA) supports clinical trials focused on efficacy of non-pharmacological interventions or noninvasive devices or clinical research to examine the impact of prevention, diagnostic, treatment or health care delivery approaches on health outcomes. Animal research is not allowed.

Clinical Trial Award (HT942526PRMRPCTA) funds projects to determine the safety or efficacy outcomes of pharmacological interventions, devices or implants on prospectively recruited human participants. Animal research, preclinical experiments, and optimization/validation of the intervention are not allowed.

Deadlines

Basic research awards: preproposals due July 16, 2026.

All other awards: preproposals due July 23, 2026.